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Here's what we have been up to!

FLOWLAB launches 'heart-ai' at the 2026 cu boulder triple-e fair!

2/28/2026

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FLOWLab is delighted to share that we launched our signature in house Outreach and Community Engagement module named HEART-AI at the recently concluded Triple-E Fair at CU Boulder. HEART-AI stands for Health Equity exposure Accessed via Real-Time AI, and is a pilot effort at bringing FLOWLab's knowledge on cardiovascular and cerebrovascular diseases to the broader community, and raising awareness about various factors associated with healthcare (risks, disparities etc.) with cardiovascular diseases as an example scenario. The work would not have been possible without key support from our collaborators, the mechanical engineering department, and - most importantly - FLOWLab's research trainees Ricardo Roopnarinesingh, Nick Rovito, Jessica Holmes, and Scott Malloy (all pictured here happily bringing HEART-AI to middle schoolers). We look forward to further growing our efforts, and continuing to bring HEART-AI to the greater Front Range community. Congratulations Team!
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Debanjan wins a college level teaming grant award!

2/17/2026

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FLOWLab is delighted to announce that PI Debanjan Mukherjee was selected as one of 3 recipients of the Spring 2026 edition of the Catalyzing Research Teaming (CRT) Grant Awards from the College of Engineering and Applied Science (CEAS) at the University of Colorado Boulder. As part of this award, Debanjan (and FLOWLab) will lead an interdisciplinary research effort on healthcare analytics and digital twins with four other investigators across multiple departments in the College. We are grateful to have been given this opportunity, and look forward to some exciting new work coming out of this endeavor. Thank you to CEAS at CU Boulder, and the reviewers!
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Jessica Wins an OUTSTANDING Teaching Assistant Award!

2/15/2026

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FLOWLab is delighted to announce that our doctoral trainee Jessica Holmes has received an Outstanding Teaching Assistant Award from the Paul M Rady Department of Mechanical Engineering for her contributions as a teaching assistant for the undergraduate fluid mechanics curriculum, and for her supportive contributions towards running a pilot on Generative AI platforms in teaching and learning in engineering classrooms (through her work as a fluid mechanics TA). Through this award, Jessica continues to build upon a successful tradition of teaching excellence amongst doctoral trainees in FLOWLab. Congratulations Jessica!
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Ricardo Wins the Geers Graduate Fellowship!

1/27/2026

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FLOWLab is delighted to announce that doctoral trainee Ricardo Roopnarinesingh has recently won the Thomas and Brenda Geers Graduate Fellowship at the University of Colorado Boulder Paul M Rady Department of Mechanical Engineering. The Geers Fellowship is awarded to recognize PhD trainees in the area of solid mechanics and fluid mechanics who exhibit extraordinary capabilities and potential. This award is in recognition of Ricardo's excellent work on developing in silico tools for embolic strokes. Congratulations Ricardo!
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FLATIRON toolkit at the CU Open Scholarship showcase!

12/20/2025

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FLOWLab was invited to present our in house open source toolkit - the FLATiron Toolkit - at the recently held CU Boulder Showcase of Open, Digital, and Public Scholarship at Norlin Library. FLATiron was one of 6 projects across the CU Boulder campus that was selected for this showcase. Lead researchers/developers Nick Rovito and Jessica Holmes were also in attendance. This is yet another example of FLOWLab's enthusiasm and commitment towards open science and public scholarship, demonstrated via tangible community standard research product. Congratulations to all trainees who have contributed towards the research and development efforts shaping FLATiron Toolkit. 
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NICK Rovito Wins The Singh Fellowship at Cu Boulder!

11/22/2025

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We are pleased to announce that FLOWLab PhD student Nick Rovito is the recipient of the 2025 Singh Graduate Fellowship, from the Paul M Rady Department of Mechanical Engineering, and the College of Engineering and Applied Sciences, at the University of Colorado Boulder. This fellowship was established to support exceptional CU Boulder mechanical engineering graduate students who are pursuing research in bioengineering or biomechanical studies. Congratulations Nick!
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New publication in physics of fluids!

10/28/2025

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We at FLOWLab are pleased to share the publication of our latest article "A stabilized finite element technique for transport phenomena within and around immersed porous bodies in flow." in Physics of Fluids. You can find the article linked HERE. 
Key takeaways:
  • We demonstrate a stabilized algorithm that can robustly resolve sharp discontinuities at boundaries of immersed porous bodies in flow using local edge-based diffusion.
  • The formulation can handle arbitrarily space-time varying or moving porous domains in non-conforming/non-fitted discretizations.
  • The methodology is reproducibly implemented for the broader community through FLOWLab's FLATiron Toolkit (available on GitHub).
Immersed porous media are abundant in biofluids. A major example in physiological settings involves blood clots - where flow and flow-mediated transport within and around heterogeneous clot aggregates remains extremely challenging to resolve in real human vascular networks. Our methodology is a step towards addressing this challenge.
The work was led by Chayut Teeraratkul, with support from our collaborators Timothy Stalker and Maurizio Tomaiuolo. If you are interested in this work, in our ongoing research portfolio on blood clots, and on FLATiron Toolkit - please DM/email me, and we can chat more!
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New publication in plos computational biology!

10/16/2025

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We are delighted to announce the publication of our latest research article "Understanding thromboembolus transport patterns in the brain for stroke in the presence of carotid artery stenosis" in PLoS Computational Biology! This work was led by doctoral trainee Ricardo Roopnarinesingh, along with our long term collaborator Michelle Leppert, and former undergrad mentee and soon to be Dr Neel Jani.

The article is available here: 
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1013269

This is a nice and impactful instance of network level nonlinearities in flow phenomena in the human body. Courtesy of this work, we now also have a set of synthetic digital twins of parameterized carotid stenosis variations (see image on the left). This work was supported by The National Institutes of Health, and we remain grateful for CU Research Computing support for the computational analyses.

Stroke and cerebrovascular flow research continues to be a mainstay of our work. Please DM/email me for collaborations or if you need additional details on the research and methods. 
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FLOWLab releases new version of FLATiron toolkit!

10/1/2025

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The FLOWLab team is happy to share the updated release of the FLATiron Toolkit - our open-source finite element library designed with a focus on multiphysics coupled simulations for flow and transport processes. The latest version of the toolkit can be accessed via our GitHub page here. or also by visiting the "Research" page of our website. Thanks to all lead contributors: Nick Rovito, Chayut Teeraratkul, and Jessica Holmes! Please reach out with any questions or collaborative project ideas. 
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FLOWLab wraps up a successful SBC 2025!

7/4/2025

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FLOWLab wrapped up a successful edition of the ASME SB3C Summer Bioengineering Conference this past week. Team PI Debanjan Mukherjee was a part of the main conference organizing committee, in the capacity of information chair. FLOWLab doctoral trainee Ricardo Roopnarinesingh presented a poster on his work on computational pipeline to integrate medical images and clinical information into in silico models. FLOWLab undergraduate trainee Alena Tucker was one of the finalists of the SBC 2025 BS Student Paper Competition, where she presented our work on in vitro modeling of drug delivery in the brain. The team also took the time to grab a quick photograph with the beautiful views that the venue Santa Ana Pueblo, New Mexico offered. 
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FLOWLab Research Featured on CU Boulder Today!

7/4/2025

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CU Boulder Today featured a wonderful story on our recent work on hemodynamics and its role in stroke for heart failure patients treated with a Left Ventricular Assist Device or LVAD! We are using hemodynamic analysis to understand why some people on LVAD support experience a stroke while others do not, and develop ways to use this information to improve LVAD therapy for heart failure. We continue to build upon this work through ongoing research at University of Colorado Boulder College of Engineering & Applied Science and UW Medicine + Heart Institute.

Check out the CU Boulder Today article linked here!

A huge thank you also to CU Boulder Today for helping get some really nice photographs of our lab, Pictured here (as well as in the article) is one of the snaps that captured some (arguably candid!) moments in the lab.

This work was made possible through many hours of brainstorming with our collaborator Jay Pal (whose support and expertise has been pivotal) and an interdisciplinary team effort with contributions from Akshita Sahni (who initiated this work in FLOWLab), Dr. Sreeparna Majee, Kelly Cao, and Erin McIntyre. My team and I also thank Amber Carlson for working with us on this story at CU Boulder Today. Lastly, we are grateful for research support from The National Institutes of Health, and the CU AB Nexus program. 
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Nick Rovito wins an Nsf GRFP award!

4/21/2025

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We are delighted to announce that FLOWLab doctoral trainee Nick Rovito is a recipient of the 2025 National Science Foundation Graduate Research Fellowship (GRFP) award! This award will support Nick's PhD research on advancing in silico modeling and quantitative analysis of vascular drug delivery techniques with a focus on thrombolytic therapy for acute ischemic stroke. This will also enable Nick to explore some of his interests in engineering education and pedagogy, enabling broader impacts of his work and building on some of FLOWLab's ongoing education and pedagogy work as well. Congratulations Nick on this well-deserved honor!
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flowlab undergraduate researcher presents at NCUR!

4/9/2025

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FLOWLab's undergraduate researcher Alena Tucker was selected to present her research at the recently held National Conference on Undergraduate Research (NCUR) at Pittsburgh. Organized by the Council on Undergraduate Research, this is a premiere scientific congregation focused on undergraduate research activities across the country. Alena presented her work on benchtop modeling of flow-mediated transport in cerebrovascular networks. This work was supported by the Discovery Learn Apprenticeship (DLA) program at the University of Colorado Boulder. The overall project also involved guidance and support from FLOWLab doctoral student Adiba Ashrafee. Alena's success is a testament to her hard work and dedication, and helps continue FLOWLab's strong record in undergraduate research training. Congratulations Alena! 
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New article on hemodynamics and stroke in patients on LVAD!

3/2/2025

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We at FLOWLab at University of Colorado Boulder College of Engineering & Applied Science are excited to share that our latest article "Hemodynamics indicates differences between patients with and without a stroke outcome after left ventricular assist device implantation." is now available online at Computers in Biology and Medicine!

Article Link: Click Here
FigShare (data+videos): Click Here
  1. We leveraged the idea of a "Digital Twin Cohort" of heart failure patients on Left Ventricular Assist Device (LVAD) support.
  2. We conducted a detailed hemodynamic assessment, comparing key flow descriptors against stroke vs no-stroke outcomes on LVAD support.
  3. Our findings indicate that post-implant hemodynamics - and - their alterations from pre-implant scenarios; can potentially reveal hidden information linked to stroke outcomes on LVAD support.
This work was made possible through funding by The National Institutes of Health (NIH) and the University of Colorado Anschutz Boulder Nexus Program. This is part of an ongoing long-term collaboration effort with Jay Pal and team at the University of Washington School of Medicine - Heart Institute; and reflects work done by several FLOWLab trainees: Akshita Sahni; Dr. Sreeparna Majee; and Kelly Cao.

There is more LVAD and mechanical circulatory support research underway at FLOWLab. Interested to learn more, collaborate, or discuss this article (or other works from our team)? Please send us an email; or reach out to our lab through our contacts page.
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NICK RoVito wins asme imece young engineer paper competition!

12/13/2024

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FLOWLab at the University of Colorado Boulder College of Engineering & Applied Science is delighted to share that our PhD trainee Nick Rovito was declared the winner (first-place) at the Young Engineer Paper (YEP) contest organized by the ASME Fluids Engineering Division (FED) at the recently concluded ASME IMECE 2024 in Portland, OR. Nick's award is in recognition of his research on in silico modeling of thrombolytic therapy for stroke; continuing on our research group's thematic emphasis on bringing advanced computational tools and models to understand physiological and pathological processes underlying diseases like stroke. This is a major recognition for student research, and we wholeheartedly congratulate Nick on his tremendous accomplishment!
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FLOwlab welcomes new members

10/16/2024

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It is a bit late into the academic year, but nevertheless it is a delight to share that FLOWLab celebrated the successful exits, and new transitions, for several members in our team. Post-doctoral scholar Sreeparna Majee, and undergraduate researchers Kelly Cao and Argudit Chauhan exited the group over the summer; while Chayut Teeraratkul completed his PhD, and transitioned over as a post-doctoral scholar. Undergraduate researcher Joshua Gregory continued to pursue an MS Thesis, joined newly by Manaswi Pulijala. Additionally, doctoral students Scott Malloy, Jessica Holmes, and Adiba Ashrafee joined the team. We are excited to continue on our research and education journey, with many new developments coming through!
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FLOWLab wins big at SB3C 2024!

6/17/2024

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FLOWLab members had a fantastic outing at the recently concluded SB3C 2024 meeting representing University of Colorado Boulder College of Engineering & Applied Science. FLOWLab doctoral trainee Chayut Teeraratkul secured First place in the PhD student paper competition for his research contribution on clot contraction mechanics. FLOWLab undergraduate trainee Argudit C. presented his research on cerebral collateral circulation as a finalist in the undergraduate paper competition. The SB3C Student Paper Competition is a hallmark of this trainee and early career friendly meeting, and winners are chosen after two rounds of rigorous scoring and reviewing. This goes to show the quality of effort that these two trainees have put in. Many congratulations to Chayut Teeraratkul for this fantastic achievement! 
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FLOWLab Celebrates Graduation and Awards!

6/11/2024

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FLOWLab was excited to celebrate a big graduation milestone this May 2024. FLOWLab had a fantastic graduation closeout with multiple happy updates reflecting the hard work of all trainees. Pictured here is FLOWLab's graduating cohort: Chayut Teeraratkul (PhD), Josh Gregory (BS-MS), Kelly Cao (BS), Argudit C. (BS), and Sarthak Samal (BS). Josh Gregory and Kelly Cao were awarded College Undergraduate Research Award, and Argudit C. was awarded a College Academic Engagement Award by the University of Colorado Boulder College of Engineering & Applied Science. In addition: Argudit C. also is a finalist at the upcoming SB3C org Undergraduate Student Paper Competition; and thereafter will be joining University of Colorado Anschutz Medical Campus for an MD. Chayut Teeraratkul got hooded as the first PhD student from FLOWLab; and is also a finalist at the upcoming SB3C org PhD Student Paper Competition. Last but not the least: FLOWLab's latest doctoral trainee Nick Rovito topped the end of semester off with an Outstanding Teaching Assistant Award in the Paul M Rady Department of Mechanical Engineering.

These successes are reflective of the efforts each of these trainees have put in; and present a snapshot of the talent and potential they will bring in to their professional domain as they continue to grow in their career. I also want to note that, in academia, successes are beautiful but infrequent at times. As we celebrate these moments, as mentors and peers, we need to also recognize the critical role of dedicated support and guidance through the difficult phases of research/training.

FLOWLab marches onwards! Congratulations to the team, graduating trainees, and their family and friends!
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latest article on cfd modeling using 3dra imaging now published!

3/18/2024

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FLOWLab is proud to announce the publication or our latest article titled "Computational Fluid Dynamic Assessment of Patients with Congenital Heart Disease from 3D Rotational Angiography" along with collaborators Jenny Zablah and Michael Shorofsky from Children's Colorado. The research presented in this article was spearheaded by talented FLOWLab undergraduate researcher Kelly Cao. We demonstrate the feasibility of utilizing a protocol that combines multi-planar reconstructed 3D rotational angiography imaging with cardiac catheterization lab hemodynamic data; to fully characterize the flow patterns in a reconstructive surgical anastomosis via CFD. You can find the article linked HERE. 
Please feel free to review our article, and reach out to us with any questions or comments! And congratulations to Kelly and our collaborators! 
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FLOWLab Had a successful Outing at APS-DFD 2023 Meeting!

11/24/2023

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FLOWLab team had an active and successful presence at the recently concluded 76th Annual Meeting of the American Physical Society Division of Fluid Dynamics meeting held at Washington DC. Our team presented a series of 5 technical talks, spanning various projects across the research program within the lab. The talks also featured our complete spectrum of trainees: undergraduate, MS, PhD, and post-doctoral. Congratulations to team FLOWLab on yet another successful APS DFD meeting!
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