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Here's what we have been up to!

New article on hemodynamics and stroke in patients on LVAD!

3/2/2025

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We at FLOWLab at University of Colorado Boulder College of Engineering & Applied Science are excited to share that our latest article "Hemodynamics indicates differences between patients with and without a stroke outcome after left ventricular assist device implantation." is now available online at Computers in Biology and Medicine!

Article Link: Click Here
FigShare (data+videos): Click Here
  1. We leveraged the idea of a "Digital Twin Cohort" of heart failure patients on Left Ventricular Assist Device (LVAD) support.
  2. We conducted a detailed hemodynamic assessment, comparing key flow descriptors against stroke vs no-stroke outcomes on LVAD support.
  3. Our findings indicate that post-implant hemodynamics - and - their alterations from pre-implant scenarios; can potentially reveal hidden information linked to stroke outcomes on LVAD support.
This work was made possible through funding by The National Institutes of Health (NIH) and the University of Colorado Anschutz Boulder Nexus Program. This is part of an ongoing long-term collaboration effort with Jay Pal and team at the University of Washington School of Medicine - Heart Institute; and reflects work done by several FLOWLab trainees: Akshita Sahni; Dr. Sreeparna Majee; and Kelly Cao.

There is more LVAD and mechanical circulatory support research underway at FLOWLab. Interested to learn more, collaborate, or discuss this article (or other works from our team)? Please send us an email; or reach out to our lab through our contacts page.
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